Key result
CKD is linked to excess arrhythmias, particularly AF, and complicates management via infection and bleeding.
Why the study?
Arrhythmias carry an increased risk of disability and premature death in patients with renal failure, where complex bidirectional interactions complicate management.
This review highlights the complex bidirectional relationship between renal dysfunction and cardiac arrhythmias, and discusses management challenges using drugs, ablation, and devices.
May heighten arrhythmia vigilance in CKD; leaves open optimal device/ablation strategies pending trials.
Arrhythmias cause disability and an increased risk of premature death in the general population but far more so in patients with renal failure. The association between the cardiac and renal systems is complex and derives in part from common causality of renal and myocardial injury from conditions including hypertension and diabetes. In many cases, there is a causal relationship, with renal dysfunction promoting arrhythmias and arrhythmias exacerbating renal dysfunction. In this review, the authors expand on the challenges faced by cardiologists in treating common and uncommon arrhythmias in patients with renal failure using pharmacological interventions, ablation and cardiac implantable device therapies. They explore the most important interactions between heart rhythm disorders and renal dysfunction while evaluating the ways in which the coexistence of renal dysfunction and cardiac arrhythmia influences the management of both.
No takes yet. Share an insight, caveat, or question.
Akhtar et al. (2022) conducted a review in Arrhythmias in Chronic Kidney Disease. Chronic kidney disease is associated with an excess of acquired arrhythmias, particularly atrial fibrillation, and complicates their management through increased risks of device infection and bleeding.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: