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Nanoparticles (NPs) have become a central focus in scientific and technological research due to their exceptional physical, chemical, and biological properties. With sizes ranging typically from 1 to 100 nanometers, these particles possess a high surface area-to-volume ratio, quantum confinement effects, and tunable surface functionalities, enabling their application in a wide variety of disciplines. Their unique characteristics have made them invaluable in medicine, environmental science, energy storage and conversion, catalysis, and advanced material design. This review provides a detailed examination of the classification, synthesis methods, characterization techniques, and diverse applications of nanoparticles. Classification is discussed based on origin (natural or engineered), composition (metallic, metal oxide, carbon-based, polymeric, and composite), and morphology (spherical, rod-like, tubular). Various synthesis routes are explored, categorized broadly into top-down and bottom-up approaches. These include physical methods like mechanical milling and laser ablation, chemical methods such as sol-gel and hydrothermal techniques, and biological or green synthesis that uses plant extracts or microorganisms to produce eco-friendly nanoparticles. A wide range of characterization techniques electron microscopy (SEM, TEM), spectroscopy (UV–Vis, FTIR, XRD), and surface area analysis (BET) are essential for evaluating the size, shape, structure, composition, and surface properties of nanoparticles. The paper also highlights key applications of nanoparticles in targeted drug delivery, cancer treatment, environmental remediation (water purification and pollutant degradation), energy devices (solar cells and batteries), and industrial processes. While the potential of nanoparticles is vast, several challenges persist, including toxicity, environmental impact, cost-effective synthesis, and regulatory issues. The review concludes by emphasizing the need for sustainable synthesis methods, improved characterization standards, and interdisciplinary research to fully harness the promise of nanotechnology for societal and industrial advancement.
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Tadesse et al. (2025) studied this question.
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