Key result
RIMA-to-RCA bypass resolves angina and restores chronotropic capacity to ~81% in anomalous RCA.
Why the study?
Anomalous RCA from the left coronary sinus is uncommon, and chronotropic limitation from sinoatrial nodal ischemia is rarely recognized.
Case Report (n=1)
A nondominant anomalous right coronary artery can present with exertional angina and chronotropic insufficiency due to sinoatrial nodal ischemia, which may be effectively managed with surgical revascularization.
May support surgical bypass in rare symptomatic anomalous RCA cases; hypothesis-generating and should not yet change practice.
BACKGROUND: Anomalous right coronary artery (RCA) from the left coronary sinus is uncommon; chronotropic limitation from sinoatrial (SA) nodal ischemia is rarely recognized. CASE SUMMARY: A 35-year-old athlete had exertional chest pain and shortness of breath. Computed tomography coronary angiography showed a left-dominant system and a nondominant anomalous RCA from the left cusp with acute takeoff, probable intramural course, and supply to the SA nodal branch. Dobutamine stress echocardiography reproduced the pain, without wall motion abnormalities but with blunted heart-rate response. After heart team discussion, right internal mammary artery-to-RCA bypass was performed. At 4 months, he was asymptomatic with restored chronotropic response. DISCUSSION: In nondominant anomalous RCA, ischemia testing may be nondiagnostic; recognizing SA nodal supply can explain chronotropic insufficiency and guide intervention. TAKE-HOME MESSAGES: Nondominant anomalous RCA may present with angina and chronotropic limitation. SA nodal ischemia can be an ischemic equivalent when regional wall motion abnormalities are absent.
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Dababneh et al. (2025) conducted a case report in Anomalous right coronary artery with sinoatrial nodal ischemia (n=1). Right internal mammary artery-to-right coronary artery bypass (CABG) was evaluated on Symptom resolution and chronotropic response. Right internal mammary artery-to-RCA bypass resolved angina and restored chronotropic capacity to 81% of predicted maximum heart rate in a patient with an anomalous right coronary artery.
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