Key result
Automated cycle length algorithm accurately processes complex AF mapping signals with ~5 ms error.
Why the study?
Reliable atrial cycle length estimation during persistent AF ablation is essential for identifying pathological zones, but remains complex due to large variability in electrogram morphology, multiple wavefronts, fragmentation, and noise.
A new cycle length estimator is proposed to reliably process complex intracardiac electrograms and estimate cycle length during atrial fibrillation ablation.
May assist real-time cycle length estimation in ablation; leaves open prospective clinical validation.
The normal electrical potential propagates throughout the atria periodically.During atrial arrhythmias its propagation is modified because the substrate is not homogeneous and new sources of punctual electrical activity appear.The periodic behavior of activation remains predominant, but becomes local in different parts of the atria.It is characterized by cycle length (CL) which measures the frequency of activation and can be computed from intracardiac bipolar electrograms (EGM) recorded by a mapping catheter during the catheter ablation procedure.The CL value of different mapped zones is an extremely important resource for physicians when performing persistent Atrial Fibrillation (AF) ablation because it helps to identify pathological zones and define the ablation strategy.Thus, a reliable estimation of the CL of atrial tissue is essential.The complexity of this task stems from the large variability in EGM morphology influenced by multiple wavefronts, fragmentation and added noise.In this work, we propose a cycle length estimator that can process the complex mapping signals recorded during atrial arrhythmias ablation and reliably provide the frequency of their periodic activity.
No takes yet. Share an insight, caveat, or question.
Veshchezerova et al. (2022) studied Atrial Fibrillation and Atrial Tachycardia (n=40). Automated cycle length estimation algorithm vs. Expert physician annotation was evaluated on Mean absolute error (MAE) of cycle length estimation. The proposed automated cycle length estimation algorithm accurately processed complex mapping signals, achieving a mean absolute error of 5.38 ms for atrial fibrillation and 2.9 ms for atrial tachycardia.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: