Why the study?
The study aimed to compare in-hospital mortality of acute myocardial infarction between males and females.
Does female sex increase the risk of in-hospital mortality in patients with acute myocardial infarction compared to male sex?
Does female sex increase the risk of in-hospital mortality in patients with acute myocardial infarction compared to male sex?
Women aged 50 to 64 years have a significantly higher risk of in-hospital mortality following STEMI compared to men of the same age.
Supports sex-specific risk assessment after STEMI; leaves open whether targeted strategies improve outcomes in women aged 50-64.
We aimed to compare in-hospital mortality (IHM) of acute myocardial infarction (AMI) between male and females. We assessed the association of sex with IHM after AMI using simple and multivariate cox regression models. Results were presented as crude and adjusted hazard ratios along with their 95% confidence interval (HR; 95% CI). Multivariable Cox regression analysis revealed females had a higher risk of death than males after ST-elevation MI (STEMI) (adjusted HR [95% CI]: 1.64 [1.15-2.36]; p = 0.007). In subgroup analysis by age group, this significantly increased risk was only observed in 50- to 64-year-old females. There were no significant differences between genders after non-STEMI and unspecified MI. Women aged 50 to 64 years had higher IHM after STEMI than men.
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Hassani et al. (2023) studied this question.
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