Key result
Malaysian adults average a ~14% 10-year risk for fatal and non-fatal CVD.
Why the study?
The study was conducted to calculate the laboratory-based and office-based Globorisk scores to predict the 10-year risk for fatal and fatal plus non-fatal CVD in the Malaysian adult population.
Cross-Sectional (n=8,253)
The Globorisk model estimates an average 10-year risk of 14% for fatal plus non-fatal CVD in the Malaysian adult population, with substantial variations by sex, race, and state.
Provides national Globorisk CVD risk estimates for Malaysia; hypothesis-generating and requires prospective validation before informing practice.
Globorisk is a novel risk prediction model that predicts cardiovascular disease (CVD) in the national population of all world countries. Using Malaysia's risk factor levels and CVD event rates, we calculated the laboratory-based and office-based risk scores to predict the 10-year risk for fatal CVD and fatal plus non-fatal CVD for the Malaysian adult population. We analysed data from 8253 participants from the 2015 nationwide Malaysian National Health and Morbidity Survey (NHMS 2015). The average risk for the 10-year fatal and fatal plus non-fatal CVD was calculated, and participants were further grouped into four categories: Low Risk (<10% risk for CVD), High-Risk A (≥10%), High-Risk B (≥20%) and High-Risk C (≥30%). Results were reported for all participants and were then stratified by sex, race, region, and state. The average risks for laboratory-based fatal CVD, laboratory-based fatal plus non-fatal CVD and office-based fatal plus non-fatal CVD were 0.07 (SD = 0.10), 0.14 (SD = 0.12) and 0.11 (SD = 0.09), respectively. There were substantial differences in terms of the sex-, race- and state-specific Globorisk risk scores obtained.
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Musa et al. (2021) conducted a cross-sectional in Cardiovascular disease risk (n=8,253). Globorisk risk prediction model was evaluated on 10-year risk of fatal CVD, laboratory-based fatal plus non-fatal CVD, and office-based fatal plus non-fatal CVD. The average 10-year risk for laboratory-based fatal CVD, laboratory-based fatal plus non-fatal CVD, and office-based fatal plus non-fatal CVD among Malaysian adults were 0.07, 0.14, and 0.11, respectively.
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