Key result
Sinus rhythm mapping shows AF patients have greater electropathology, particularly Bachmann's bundle conduction disorders.
Why the study?
Specific features of AF-related electropathology remain unknown, making it essential to quantify atrial tissue electrophysiological properties and examine variations during sinus rhythm to evaluate AF risk and therapy effectiveness.
Does sinus rhythm mapping identify atrial fibrillation-related electropathology and patients at risk for early onset or progression of atrial fibrillation?
Does sinus rhythm mapping identify atrial fibrillation-related electropathology and patients at risk for early onset or progression of atrial fibrillation?
Quantifying atrial electrophysiological properties during sinus rhythm may help identify patients at risk for early onset or progression of atrial fibrillation.
Answers are grounded in this paper and cite their sources.
May aid AF risk stratification via sinus rhythm mapping; leaves open prospective validation before clinical use.
Progression of AF is accompanied by structural and electrical remodelling, resulting in complex electrical conduction disorders. This is defined as electropathology and it increases with the progression of AF. The severity of electropathology, thus, defines the stage of AF and is a major determinant of effectiveness of AF therapy. As specific features of AF-related electropathology are still unknown, it is essential to first quantify the electrophysiological properties of atrial tissue and then to examine the inter- and intra-individual variation during normal sinus rhythm. Comparison of these parameters between patients with and without a history of AF unravels quantified electrophysiological features that are specific to AF patients. This can help to identify patients at risk for early onset or progression of AF. This review summarises current knowledge on quantified features of atrial electrophysiological properties during sinus rhythm and discusses its relevance in identifying AF-related electropathology.
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Schie et al. (2022) conducted a review in Atrial Fibrillation. Sinus rhythm mapping was evaluated. Sinus rhythm mapping reveals that patients with atrial fibrillation have more electropathology, particularly conduction disorders at Bachmann's bundle, compared to patients without atrial fibrillation.
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