Key result
Neither ECG score nor CT pulmonary angiographic clot burden at diagnosis showed a statistically significant association with 12-month all-cause mortality in patients with pulmonary embolism.
Why the study?
Does CT pulmonary angiographic clot burden score or ECG score at diagnosis correlate with 12-month mortality in patients with pulmonary embolism?
Cohort (n=105)
Does CT pulmonary angiographic clot burden score or ECG score at diagnosis correlate with 12-month mortality in patients with pulmonary embolism?
p-value: p=0.65, <0.73
Neither ECG score nor CT pulmonary angiographic clot burden score at diagnosis significantly predicts 12-month mortality in patients with pulmonary embolism.
ECG and CT clot burden scores should not guide 12-month mortality risk assessment in PE; leaves open validation of alternative prognostic tools.
OBJECTIVE: The purpose of this study was to establish whether a correlation exists between the CT pulmonary angiographic clot burden score, the ECG score at diagnosis, and the 12-month mortality rate among patients diagnosed with pulmonary embolism. SUBJECTS AND METHODS: A total of 523 consecutive patients who underwent CT pulmonary angiography for a suspected moderate to high pretest probability of pulmonary embolism were recruited from March 2003 to October 2004. There were 105 patients with positive CT pulmonary angiography examinations. Two consultant respiratory physicians and two consultant radiologists independently and prospectively calculated an ECG score and a quantified pulmonary artery clot burden, respectively. Twelve-month follow-up was completed in all patients. RESULTS: The mean ECG score was 2.36 (SD, 2.84) and the mean clot burden score percentage was 23.74% (16.8%). Poor correlation (r = 0.09) was seen between the average ECG score and the average clot burden score percentage (p = 0.39) at diagnosis. Thirteen patients had died at the 12-month follow-up. The mean ECG score for those patients who were alive was 2.4 (2.91) and for those who had died was 2.03 (2.34) at 12 months (p = 0.65). The mean clot burden score percentage for those patients who were alive was 24% (17%) and for those who had died was 22.1% (15.7%) at 12 months (p < 0.73). CONCLUSION: No statistically significant association was seen between ECG score and CT pulmonary angiographic clot burden at diagnosis and the 12-month all-cause mortality rate of patients diagnosed with pulmonary embolism.
No takes yet. Share an insight, caveat, or question.
Subramaniam et al. (2008) conducted a cohort in Pulmonary embolism (n=105). CT pulmonary angiographic clot burden score and ECG score was evaluated on 12-month all-cause mortality rate (p=0.65, <0.73). Neither ECG score nor CT pulmonary angiographic clot burden at diagnosis showed a statistically significant association with 12-month all-cause mortality in patients with pulmonary embolism.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: