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January 1, 2015Open Access

Transcatheter Aortic Valve Implantation (TAVI) for the Treatment of Aortic Valve Stenosis: a Systematic Review

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Why the study?

Does TAVI improve clinical outcomes compared to medical management or SAVR in patients with severe symptomatic aortic stenosis who are unsuitable or at high risk for surgery?

Population

Patients with severe symptomatic aortic stenosis who are unsuitable for or at high risk to undergo surgical…

Comparison

Transcatheter aortic valve implantation using… vs Medical management or surgical aortic valve…

Design

Systematic_review

Follow-up

Up to 1 year

Authors

PSPedro P Sad

Discussion

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Member takes

Overview

Supports TAVI over medical management in high-risk severe AS; reinforces survival data from prior RCTs in systematic evidence.

Structured PICO

Does TAVI improve clinical outcomes compared to medical management or SAVR in patients with severe symptomatic aortic stenosis who are unsuitable or at high risk for surgery?

P
Population
Patients with severe symptomatic aortic stenosis who are unsuitable for or at high risk to undergo surgical aortic valve replacement (SAVR) (56 studies included)
I
Intervention
Transcatheter aortic valve implantation (TAVI) using transfemoral (TF) or transapical (TA) approaches
C
Comparator
Medical management (MM) or surgical aortic valve replacement (SAVR)
O
Outcome
Feasibility, safety, efficacy and clinical effectiveness of TAVI

TAVI is a safe and effective treatment for severe aortic stenosis in patients unsuitable for or at high risk for SAVR, offering improved 1-year survival compared to medical management.

Limitations

  • Shortcomings in the evidence on long term outcomes make it difficult to determine the effectiveness of TAVI in high risk patients who may be candidates for surgery

Cite This Study

Pedro P Sad (2015) studied this question.

synapsesocial.com/papers/6a0f2b1a11edbd3546bdc73ahttps://doi.org/10.7939/r3sq20
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