Key result
High filling pressure and low cardiac output predicted a severe disease course in 106 patients with chronic myocardial disease followed for 2-12 years, whereas increased LV wall thickness was benign.
Why the study?
Do baseline haemodynamic findings predict the clinical course in patients with chronic myocardial disease?
Cohort (n=106)
Do baseline haemodynamic findings predict the clinical course in patients with chronic myocardial disease?
Baseline haemodynamic parameters, specifically filling pressure, cardiac output, and pulmonary resistance, serve as important prognostic indicators in patients with chronic myocardial disease.
May support hemodynamic risk stratification in chronic myocardial disease; leaves open therapeutic implications today.
Haemodynamic findings in 106 patients with chronic myocardial disease have been related to the course of the disease during a follow-up period of 2-12 years. A high filling pressure, especially when combined with low cardiac output, suggested a severe development. The worst outlook was noted in patients who in addition had raised pulmonary arteriolar resistance. On the other hand, a low filling pressure even if cardiac output was reduced, was generally associated with a more benign course. An increase in left ventricular wall thickness as determined angiographically suggested a better outlook than normal wall thickness.
No takes yet. Share an insight, caveat, or question.
Hatle et al. (1976) conducted a cohort in Chronic myocardial disease (n=106). Haemodynamic assessment was evaluated on Course of the disease. High filling pressure and low cardiac output predicted a severe disease course in 106 patients with chronic myocardial disease followed for 2-12 years, whereas increased LV wall thickness was benign.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: