Detection of Nucleic Acids Using Enzyme‐Catalyzed Template‐Guided Deposition of Polyaniline

An electrochemical procedure for the detection of nucleic acids is realized by utilizing polyaniline as a signal generator for the transduction of nucleic acid hybridization events (see figure). The unique combination of enzymatic amplification and template-guided deposition can be used in conjunction with other detection techniques, and the sensitivity of the biosensor increases with increasing time. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2089/2007/c1090_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.