Echocardiographic assessment of 1095 healthy Argentinean children and adolescents (5-24 years) established age- and sex-specific percentile curves for left atrial diameter and volume.
Cross-Sectional (n=1,095)
This study provides the largest Argentinean database of sex- and age-specific percentile curves for left atrial size in healthy children and adolescents, aiding in accurate echocardiographic interpretation.
Background Despite the clinical utility of echocardiography to measure left atrial ( LA ) structure and function, there are scarcities of data about the percentiles of LA diameter ( LA D ), LA volume ( LA VOL ), and LA volume indexed by body surface area ( LA VOL / BSA ) from prospective population‐based studies in healthy children and adolescents from the Southern Cone of Latin America. Methods Echocardiographic studies were obtained in 1095 healthy subjects nonexposed to cardiovascular risk factors (5–24 years). Age‐ and sex‐specific reference values of LA D , LA VOL , and LA VOL / BSA were generated using parametric regression based on fractional polynomials. Results After covariate analysis (ie, adjusting by age, body surface area), specific sex‐specific percentiles were evidenced as necessaries. Age‐ and sex‐specific 1st, 2.5th, 5th, 10th, 25th, 50th, 75th, 90th, 95th, 97.5th, and 99th percentile and curves were reported. Our percentiles showed high concordance and complementarity with what was previously reported for the population of North American, European, and Asiatic Populations. Conclusions In children and adolescents, the interpretation of the LA size requires sex‐related percentiles. This study provides the largest Argentinean database concerning percentile curves of LA D , LA VOL , and LA VOL / BSA obtained in healthy children and adolescents. These data are valuable in that they provide values with which data of populations of children, adolescents, and young adults can be compared.
Díaz et al. (Fri,) conducted a cross-sectional in Healthy children and adolescents (n=1,095). Echocardiographic measurement of left atrial size was evaluated on Age- and sex-specific reference values of LAD, LAVOL, and LAVOL/BSA. Echocardiographic assessment of 1095 healthy Argentinean children and adolescents (5-24 years) established age- and sex-specific percentile curves for left atrial diameter and volume.