Why the study?
Cardiovascular disease accounts for nearly half of all deaths in Poland, and the impact of prehospital treatment duration and delays on discharge LVEF and in-hospital mortality in STEMI patients was assessed.
Does prolonged prehospital system delay increase in-hospital mortality and reduce LVEF in STEMI patients?
Observational (n=573)
No
Does prolonged prehospital system delay increase in-hospital mortality and reduce LVEF in STEMI patients?
While unadjusted analyses suggest prehospital delays increase mortality and reduce LVEF in STEMI patients, these effects lose statistical significance after adjusting for baseline confounders like age and shock.
No independent mortality link after adjustment; hypothesis-generating for prehospital delays in STEMI, needing prospective trials.
BACKGROUND: Cardiovascular disease accounts for nearly half of all deaths in Poland. The aim of this study was to assess both the duration and the delays of prehospital treatment in ST-segment elevation myocardial infarction (STEMI) patients and how it impacts left ventricle ejection fraction (LVEF) measured at the time of discharge and the frequency of in-hospital patient mortality. METHODS: This study retrospectively analyzed medical records from January 2011 to December 2015 (excluding the year 2013) of 573 patients who were transported to a hospital with a diagnosis of STEMI. RESULTS: The mean time of prehospital system delays was 59 min with a maximum time of 152 min and a minimum time of 23 min. The relationship between reduced LVEF (< 55%) and in-hospital patient mortality and the relationship between length of time from first medical contact (FMC) to hospital admission was analysed in 515 respondents. Extending the time of FMC to hospital admission by 1 min increased the chances of lowering LVEF by 2% (95% CI: 1.004-1.041) and increased the chances of death by 2% (95% CI: 1.002-1.04) in STEMI patients. CONCLUSIONS: This study emphasised how vital it is to minimise time spent with STEMI patients at the scene of their cardiovascular event by performing an ECG as quickly as possible and by immediately transporting the patient to the hospital with the targeted treatment. This may lead to the implementation of additional training in the field of ECG interpretation, increase the prevalence of teletransmission systems, and improve communication between Emergency Medical Services (EMS) and catheterization laboratories ultimately reducing patient mortality.
No takes yet. Share an insight, caveat, or question.
Żurowska-Wolak et al. (2019) conducted an observational in ST-segment elevation myocardial infarction (STEMI) (n=573). Prehospital system delay (time from FMC to hospital admission) was evaluated on In-hospital death (OR 1.022, 95% CI 1.002-1.04).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: