Key result
Strain-encoded MR imaging identified a greater extent of dysfunctional myocardium than delayed contrast-enhanced MR (P<.05) and strongly correlated with 3D tagged MR imaging (r=0.75, P<.001).
Why the study?
Does strain-encoded MR imaging accurately measure systolic myocardial strain compared to delayed contrast-enhanced MR imaging in patients with myocardial infarction and healthy volunteers?
Observational (n=14)
Does strain-encoded MR imaging accurately measure systolic myocardial strain compared to delayed contrast-enhanced MR imaging in patients with myocardial infarction and healthy volunteers?
Effect estimate: r = 0.75
p-value: p=< .001
Strain-encoded MR imaging provides spatially resolved measurement of myocardial strain without postprocessing, potentially improving routine evaluation of myocardial viability.
Strain-encoded MR may identify more dysfunctional myocardium than delayed enhancement; hypothesis-generating for viability assessment pending prospective validation.
Strain-encoded magnetic resonance (MR) imaging was prospectively evaluated for direct imaging of systolic myocardial strain and compared with cross-registered delayed contrast material-enhanced MR imaging in five healthy volunteers and nine patients with infarction. Local contractile performance was decreased in infarcted myocardium versus that in remote and adjacent myocardium (P < .01) and in adjacent versus remote myocardium (P < .05). The extent of dysfunctional myocardium, as assessed with strain-encoded MR imaging, was greater than that of hyperenhancement, as assessed with delayed contrast-enhanced MR imaging (P < .05). Strain values obtained with strain-encoded MR imaging were strongly correlated with those obtained with three-dimensional tagged MR imaging (r = 0.75, P < .001). Strain-encoded MR imaging provides spatially resolved (1.5 x 2.5-mm) imaging and measurement of myocardial strain in humans without the need for postprocessing, which may improve routine comprehensive evaluation of myocardial viability.
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Garot et al. (2004) conducted an observational in Myocardial infarction (n=14). Strain-encoded MR imaging vs. Delayed contrast-enhanced MR imaging and three-dimensional tagged MR imaging was evaluated on Correlation of strain values between strain-encoded MR imaging and three-dimensional tagged MR imaging (r = 0.75, p=< .001). Strain-encoded MR imaging identified a greater extent of dysfunctional myocardium than delayed contrast-enhanced MR (P<.05) and strongly correlated with 3D tagged MR imaging (r=0.75, P<.001).
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