Key result
A review of experimental evidence on antiarrhythmic drugs highlights fundamental mechanisms of proarrhythmia, providing insights for developing safer antiarrhythmic compounds.
Understanding the fundamental mechanisms of proarrhythmia is essential for developing newer and safer antiarrhythmic compounds.
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Current antiarrhythmic prescribing warrants caution for proarrhythmia; leaves open mechanism-guided development of safer agents.
Stanley Nattel (1998) conducted a review in Arrhythmia. Antiarrhythmic drugs was evaluated. A review of experimental evidence on antiarrhythmic drugs highlights fundamental mechanisms of proarrhythmia, providing insights for developing safer antiarrhythmic compounds.
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