Catheter ablation of atrial fibrillation resulted in a lower risk of cerebrovascular accidents and dementia compared with medical management alone at long-term follow-up.
Meta-Analysis
Does catheter ablation reduce the risk of cerebrovascular accidents and dementia in patients with atrial fibrillation compared to medical management alone?
Catheter ablation for atrial fibrillation is associated with a lower long-term risk of cerebrovascular accidents and dementia compared to medical management alone.
Background: Catheter ablation (CA) of atrial fibrillation (AF) has been proven to benefit patients with symptomatic AF and heart failure. However, the data on neurological outcomes including cerebrovascular accidents (CVA) and dementia remain controversial. Objective: We aimed to determine the effect of CA on neurological events during long-term follow-up. Methods: We performed a systematic review and meta-analysis of patients with AF who underwent CA of AF. The MEDLINE, EMBASE, and Web of Science databases were comprehensively searched from inception to January 2024. Studies that reported incidence of CVA and dementia in patients with AF were. Data from each study were combined by a random-effects model. The results were reported in risk ratios with 95% confidence intervals (CIs). Results: = 97%). Conclusion: CA of AF resulted in lower risk of CVA and dementia compared with medical management alone at long-term follow-up.
Al‐Sadawi et al. (Sat,) conducted a meta-analysis in Atrial fibrillation. Catheter ablation vs. Medical management alone was evaluated on Cerebrovascular accidents (CVA) and dementia. Catheter ablation of atrial fibrillation resulted in a lower risk of cerebrovascular accidents and dementia compared with medical management alone at long-term follow-up.