Why the study?
Does cardiac surgery improve outcomes in patients aged 65 years and older with coronary artery disease?
Does cardiac surgery improve outcomes in patients aged 65 years and older with coronary artery disease?
Cardiac surgery for coronary artery disease in patients aged 65 and older is associated with acceptable mortality and significant clinical improvement, suggesting advanced age alone is not a contraindication.
Advanced age alone may not contraindicate surgery in elderly CAD; leaves open need for RCTs to confirm benefit.
One hundred patients aged 65 years and older underwent operation for coronary artery disease, its complications, or both. Seventy-eight patients had saphenous vein bypass grafts only. The remainder included segmentectomies, aneurysmectomies, or valve replacement combined with grafts, or aneurysmectomies alone. Significant complications were rare; severe arrhythmias and low cardiac output were the most frequent serious complications and occurred in nine patients. A total of 178 bypass grafts were performed on 89 patients. There were six early deaths and four late deaths for a total overall mortality of 10%. All deaths were in patients with end-stage coronary artery disease and, with one exception, death was due to this advanced disease. Follow-up in 83 patients revealed a significant improvement in 77 patients (93%). Advanced age alone is not a contraindication to surgery for coronary artery disease.
No takes yet. Share an insight, caveat, or question.
Gilbert W. Ashor (1973) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: