Why the study?
Does isoflurane affect conduction velocity and Vmax in guinea pig papillary muscles compared to halothane and enflurane?
Population
Guinea pig papillary muscles
Comparison
Isoflurane (at 1.5 and 2.0 MAC) vs Halothane and enflurane at equi-MAC concentrations
Design
Preclinical
Authors
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Isoflurane may slow conduction less in this model; leaves open any clinical preference in conduction disease.
Does isoflurane affect conduction velocity and Vmax in guinea pig papillary muscles compared to halothane and enflurane?
Isoflurane slows intraventricular conduction less than halothane and enflurane, suggesting it may be a safer anesthetic for patients with intraventricular conduction abnormalities.
Ozaki et al. (1990) studied this question.
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