Key result
Review evaluates current evidence for intrinsic cardiac autonomic nervous system neuromodulation in AF management.
Why the study?
Imbalances in the intrinsic cardiac autonomic nervous system contribute to the arrhythmogenesis of AF, prompting interest in summarizing evidence on its neuromodulation.
Does neuromodulation of the intrinsic cardiac autonomic nervous system improve outcomes in patients with atrial fibrillation?
Does neuromodulation of the intrinsic cardiac autonomic nervous system improve outcomes in patients with atrial fibrillation?
This review summarizes the current evidence on neuromodulation of the intrinsic cardiac autonomic nervous system for the management of atrial fibrillation.
Neuromodulation of the intrinsic cardiac autonomic nervous system should not yet change AF practice; leaves open its efficacy pending prospective trials.
Atrial fibrillation (AF) is the most common supraventricular arrhythmia that is linked with higher cardiovascular morbidity and mortality. Recent evidence has demonstrated that catheter-based pulmonary vein isolation (PVI) is not only a viable alternative but may be superior to antiarrhythmic drug therapy for long-term freedom from symptomatic AF episodes, a reduction in the arrhythmia burden, and healthcare resource utilization with a similar risk of adverse events. The intrinsic cardiac autonomic nervous system (ANS) has a significant influence on the structural and electrical milieu, and imbalances in the ANS may contribute to the arrhythmogenesis of AF in some individuals. There is now increasing scientific and clinical interest in various aspects of neuromodulation of intrinsic cardiac ANS, including mapping techniques, ablation methods, and patient selection. In the present review, we aimed to summarize and critically appraise the currently available evidence for the neuromodulation of intrinsic cardiac ANS in AF.
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Aksu et al. (2023) conducted a review in Atrial fibrillation. Neuromodulation of intrinsic cardiac autonomic nervous system was evaluated. This review summarizes and critically appraises the currently available evidence for the neuromodulation of the intrinsic cardiac autonomic nervous system in the management of atrial fibrillation.
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