Key result
Sex-specific body fat distribution and genetics link to CVD risk independent of overall adiposity.
Why the study?
Body fat distribution is more closely associated with cardiovascular disease risk than total adiposity, and understanding sex determinations on body fat distribution may improve CVD prevention and treatment.
Understanding sex differences in body fat distribution and adiposity may aid in improving the prevention and treatment of cardiovascular diseases.
May inform sex-specific CVD risk stratification; leaves open causal mechanisms and targeted interventions.
Body fat distribution is a well-established predictor of adverse medical outcomes, independent of overall adiposity. Studying body fat distribution sheds insights into the causes of obesity and provides valuable information about the development of various comorbidities. Compared to total adiposity, body fat distribution is more closely associated with risks of cardiovascular diseases. The present review specifically focuses on the sexual dimorphism in body fat distribution, the biological clues, as well as the genetic traits that are distinct from overall obesity. Understanding the sex determinations on body fat distribution and adiposity will aid in the improvement of the prevention and treatment of cardiovascular diseases (CVD).
No takes yet. Share an insight, caveat, or question.
Li et al. (2022) conducted a review in Cardiovascular diseases and adiposity. Sexual dimorphism in body fat distribution and its distinct genetic traits are closely associated with cardiovascular disease risk, independent of overall adiposity.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: