Randomized trial investigates natural products targeting ferroptosis to treat sepsis-related organ injuries, highlighting novel therapy avenues.
Key Points
This research aims to explore the role of ferroptosis in sepsis and the therapeutic potential of natural products in treating associated organ injuries.
Summarized mechanisms of ferroptosis in sepsis
Identified natural products targeting ferroptosis
Reviewed preclinical investigations and clinical data
Natural products demonstrate efficacy in mediating ferroptosis for sepsis treatment
Evidence mainly from preclinical studies
Clinical data remain insufficient to support widespread use