Identifies HDAC7 inhibition to enhance ATF3 tumor suppression in colorectal cancer, suggesting a new therapeutic approach.
. Our work identifies HDAC7 as a molecular mediator that governs ATF3's functional plasticity through competitive cofactor recruitment, positioning HDAC7 inhibition as a therapeutic strategy to reactivate ATF3-mediated tumor suppression in CRC.
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Wang et al. (2026) studied this question.
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