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May 22, 2026VirulenceOpen Access

Surveillance and biological characterization of H3 subtype avian influenza viruses in Eastern China

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Authors

XMXinyu MiaoXZXinyi ZhaoNZNan Zhang

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Overview

Randomized trial investigates transmission characteristics of H3 subtype avian influenza viruses, highlighting potential cross-species transmission implications.

Key Points

  • The aim is to explore the genetic evolution and pathogenic features of H3 subtype avian influenza viruses in Eastern China.
  • Analyzed seven H3 subtype avian influenza virus isolates from 2014 to 2021, including five H3N2, one H3N3, and one H3N6 strain.
  • Conducted phylogenetic analysis to assess genetic relationships and reassortment events.
  • Evaluated pathogenicity and transmission efficiency in various animal species.
  • All isolates belonged to the Eurasian lineage with extensive reassortment noted.
  • H3N2 subtype exhibited dual receptor-binding properties, showing higher transmission efficiency in guinea pigs.
  • Despite low pathogenicity in tested species, findings indicate potential for cross-species transmission.

Cite This Study

Miao et al. (2026) studied this question.

synapsesocial.com/papers/6a0ff2a8d674f7c03778b37ahttps://doi.org/10.1080/21505594.2026.2673657
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