Case report shows continuous methylene blue infusion improves methemoglobinemia in a young child, suggesting effective treatment for severe cases.
Acquired methemoglobinemia is a rare and potentially lethal complication of several oxidizing agents, with ingestions reported in patients of various demographics.Here, we present a 30-month-old patient with sodium chlorite-induced methemoglobinemia that was refractory to initial intermittent infusions of methylene blue and ultimately required continuous infusion of the antidote.The hospital course was complicated by hemolytic anemia requiring blood transfusion, with eventual improvement in laboratory testing and clinical presentation.
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Ming et al. (2026) studied this question.
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