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This research investigates the antimicrobial and cytotoxic properties of various medicinal plant extracts against multidrug-resistant pathogens.

Phyto-Therapeutic Potential of Medicinal Plant Extracts against MDR Pathogens and Their Cytotoxicity

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This research investigates the antimicrobial and cytotoxic properties of various medicinal plant extracts against multidrug-resistant pathogens.
Eight medicinal plants were tested using disc diffusion method against E. coli, S. aureus, and B. subtilis.
Cytotoxicity was assessed via MTT assay on MDA-MB-231 breast cancer cell lines.
Crude extracts were prepared through maceration using aqueous, methanol, and ethanol solvents.
Anogeissus latifolia exhibited the highest antimicrobial activity against E. coli (28 ± 0.58 mm).
Aristolochia rotunda showed the highest antimicrobial activity against B. subtilis (32 ± 1.23 mm) and S. aureus (35 ± 1.02 mm).
Viola odorata and Acacia nilotica demonstrated the highest cytotoxicity against MDA-MD-231 cells at 1% and 6%, respectively.

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Randomized trial tests antimicrobial and cytotoxic effects of plant extracts against MDR pathogens, suggesting promising alternatives.

Iqtedar et al. (2026) studied this question.

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