Demonstrates high enantioselectivities in cyclopropane formation from aldehydes, implying a novel synthetic approach.
A synergistic combination of organocatalysis and N-Iodosuccinimide allows for the asymmetric formation of cyclopropanes through the direct C-H activation of aldehydes onMichael acceptors. This process achieves high enantioselectivities ranging from...
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Canesi et al. (2026) studied this question.
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