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January 1, 2026RSC AdvancesOpen Access

Photoinactivation of S. aureus biofilms using porphyrin conjugates with green-synthesized TiO ₂ immobilized on waste polystyrene

Nonkululeko Malomane Nkgameleng K. Mokhonoana Christian I. Nkanga Ojodomo J. Achadu Richard M. Moutloali Muthumuni Managa

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Key Points

This research aims to investigate an effective method for inactivating S. aureus biofilms using photoinactivation techniques.
Utilized porphyrin conjugates with green-synthesized TiO2 immobilized on waste polystyrene.
Examined the photoinactivation effects on S. aureus biofilms in simulated water storage conditions.
Achieved significant reduction of S. aureus biofilm viability post-treatment.
Demonstrated enhanced effectiveness of TiO2 under light exposure compared to conventional chlorine disinfection.

Implication

Demonstrates effective photoinactivation of biofilms in water systems, suggesting a novel approach to address waterborne infections.

Abstract

Waterborne infections remain a global concern, exacerbated by biofilms in water storage systems that resist chlorine disinfection.

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Cite This Study

Malomane et al. (2026) studied this question.

synapsesocial.com/papers/6a0ff3c0d674f7c03778c968 https://doi.org/10.1039/d6ra00069j

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Photoinactivation of Escherichia coli and Staphylococcus aureus using Porphyrin-CuInS2/ZnS quantum dot conjugates immobilized on Mesoporous Silica2024 · 6 citations
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3Potential of Photodynamic Inactivation with Porphyrins Against Planktonic and Biofilm Forms of Antibiotic-Resistant Wound Infection Pathogens2025
4Refining antimicrobial photodynamic therapy: effect of charge distribution and central metal ion in fluorinated porphyrins on effective control of planktonic and biofilm bacterial forms2024 · 26 citations
5Photosensitized TiO2 nanomaterials for visible-light antimicrobial photodynamic inactivationOriginal Research · 2026

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Detailed Insight into Photocatalytic Inactivation of Pathogenic Bacteria in the Presence of Visible-Light-Active Multicomponent Photocatalysts2024
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