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May 22, 2026Open Access

Microtubule Coherence Index: A Minimal Excitable Lattice Model of Conformational Propagation and Phase Boundary Collapse

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Authors

TMThomas S. Mitchell

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Overview

Randomized trial explores conformational propagation in microtubule systems, indicating different dynamics than tissue networks.

Key Points

  • This research aims to explore the dynamics of conformational propagation and phase boundary collapse in microtubules using a new computational model.
  • Developed a one-dimensional lattice model using αβ-tubulin dimers and classical dynamics.
  • Analyzed the logistic phase transitions between coherent and fragmented states.
  • Tested the model against previously established tissue coherence indices.
  • Demonstrated a sharp logistic transition between coherent and fragmented propagation (no specific rates provided).
  • Found significant divergence in critical thresholds from tissue-level behavior, indicating distinct dynamical regimes.
  • Identified negative results that show previous models do not align with observed thresholds, highlighting differences in dynamical universality classes.

Cite This Study

Thomas S. Mitchell (2026) studied this question.

synapsesocial.com/papers/6a0ff42fd674f7c03778d5b2https://doi.org/10.5281/zenodo.20302161
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