Protective Effect of Silymarin Against Gentamicin-Induced Oxidative Stress in Mice

View at Publisher

Ask AI

Bookmark

Share

Key Points

The aim is to assess how silymarin protects against oxidative stress and renal damage caused by gentamicin in mice.
Evaluated the protective effects of silymarin in mice with gentamicin-induced oxidative stress.
Measured biochemical markers and histopathological changes to assess renal damage.
Determined glutathione (GSH) levels pre- and post-treatment with silymarin.
Gentamicin significantly reduced GSH levels in the renal tissue, indicating impaired antioxidant defense.
Silymarin treatment restored GSH levels, suggesting its protective role against oxidative stress.
Histopathological analysis showed reduced renal damage in silymarin-treated groups compared to gentamicin-only groups.

We only have this paper's title and publication details.

Evaluates silymarin's ability to reduce oxidative stress and renal damage in mice, indicating its potential for therapeutic use.

No takes yet. Share an insight, caveat, or question.

Başer et al. (2026) studied this question.

View at Publisher

Ask AI

Bookmark

Share