Key result
Higher PM 2.5 is linked to ~56% greater IHD risk, but neighborhood walkability mitigates it.
Why the study?
Does neighborhood walkability interact with PM 2.5 exposure to affect the risk of incident ischemic heart disease?
Population
47,516 participants in a prospective cohort in Yinzhou, Ningbo, China
Design
Cohort
Follow-up
median 5.14 years
Authors
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Higher neighborhood walkability is associated with a reduced risk of ischemic heart disease and attenuates the adverse cardiovascular effects of long-term PM 2.5 exposure.
Cohort (n=47,516)
Does neighborhood walkability interact with PM 2.5 exposure to affect the risk of incident ischemic heart disease?
Hazard Ratio: 1.56 (95% CI 1.34–1.81)
Higher neighborhood walkability is associated with a reduced risk of ischemic heart disease and attenuates the adverse cardiovascular effects of long-term PM 2.5 exposure.
Zhang et al. (2024) conducted a cohort in ischemic heart disease (n=47,516). PM 2.5 exposure and walkability vs. Lower exposure levels was evaluated on incident ischemic heart disease (HR 1.56, 95% CI 1.34-1.81). A 10 μg/m3 increase in PM 2.5 elevated ischemic heart disease risk (HR 1.56; 95% CI 1.34-1.81), while higher walkability mitigated this adverse effect (P interaction = 0.019).
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