Phenylacetylene and 1-pentyne derivatives containing aminated tetraphenylethene (TPE) units 1 and 2 are synthesized. The TPE-functionalized luminogens are nonemissive in dilute solutions but luminescent as solid aggregates, showing a novel behavior of aggregation-induced emission (AIE). The monomers are polymerized to their corresponding polymers P1 and P2 with an E conformation by organorhodium catalysts, although Rh-catalyzed polymerizations normally yield Z-rich polyacetylenes. Whereas P1 fluoresces faintly in THF, its light emission is enhanced by aggregation in aqueous media, exhibiting an aggregation-induced emission enhancement (AIEE) effect. On the other hand, P2 is AIE active: the emission of its nanoaggregates suspended in 90% aqueous mixture is ∼57-fold stronger than that of its solution in THF. A novel superamplification effect is observed in the emission quenching of P2 nanoaggregates by picric acid (PA): the quenching constant (KSV) is nonlinearly increased with the quencher concentration and reaches a very high value in the high [PA] region (KSV ∼ 350 000 M−1). P1 and P2 are transformed to conjugated polyelectrolytes P1+ and P2+ via ionization by hydrochloric acid. P1+ readily hybridizes with carbon nanotubes, affording functionalized P1+/nanotube hybrids with good water miscibility. Emission of P2+ in aqueous buffer is boosted when it binds to bovine serum albumin (BSA), allowing the polymer to work as a sensitive bioprobe for BSA quantitation at ultralow protein concentration (0−0.6 ppm).
No takes yet. Share an insight, caveat, or question.
Yuan et al. (2009) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: