Key result
ViRaTonPBS system shows no antiviral activity against human adenovirus type 5.
Why the study?
Surface-mediated viral transmission is critical, and traditional disinfection methods require repeated application, motivating continuous contact-free disinfection options.
Does the ViRaTonPBS system reduce viral infectivity of enveloped and non-enveloped viruses on surfaces?
Does the ViRaTonPBS system reduce viral infectivity of enveloped and non-enveloped viruses on surfaces?
The ViRaTonPBS system lacks efficacy against certain non-enveloped viruses like HAdV-5, despite potential for continuous disinfection in public environments.
May support further antiviral exploration; leaves open clinical utility pending rigorous trials.
BACKGROUND: Surface-mediated transmission is a critical pathway for viral spread. Traditional disinfection methods can be effective but require repeated application. AIM: ) system designed to offer continuous, contact-free disinfection in real-world settings by delivering hyper-charged photoelectrons. METHOD: was tested against enveloped viruses (influenza virus type A [H1N1], and Herpes simplex virus type 1 [HSV-1]) and non-enveloped viruses (murine norovirus type 1 [MNV-1] and human adenovirus type 5 [HAdV-5]) on stainless steel, glass, and laminate surfaces at distances of 1 and 5 m and exposure times of 5, 15, and 30 min. Viral infectivity was assessed using 50% tissue culture inhibitory assay/mL and plaque assays. RESULT: showed no significant antiviral activity against HAdV-5 under any test condition, including at 0.5 m for 45 min, indicating that its effectiveness may be limited against certain non-enveloped viruses. CONCLUSION: Overall, this system showed strong potential for continuous use in healthcare, transportation, educational, and other indoor public environments.
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Urmi et al. (2026) studied Viral contamination on surfaces. ViRaTonPBS system was evaluated on Viral infectivity. The ViRaTonPBS system showed no significant antiviral activity against human adenovirus type 5 under any test condition, indicating limited effectiveness against certain non-enveloped viruses.
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