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March 15, 2002Journal of Clinical InvestigationOpen Access

Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite

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MZMing-Hui ZouGeorgia State UniversityCSChaomei ShiSanofi (France)RCRichard A. CohenAchva Academic College

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Zou et al. (2002) studied this question.

synapsesocial.com/papers/6a10177ffb2817e31dfcedd5https://doi.org/10.1172/jci14442
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Also Consider

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  3. 3Acute Amelioration of Diabetic Endothelial Dysfunction with a Derivative of the Nitric Oxide Synthase Cofactor, Tetrahydrobiopterin1997 · 226 citations
  4. 4Inactivation of the Inducible Nitric Oxide Synthase by Peroxynitrite1997 · 47 citations
  5. 5Role of Bound Zinc in Dimer Stabilization but Not Enzyme Activity of Neuronal Nitric-oxide Synthase2000 · 109 citations