Key result
Systolic time intervals (PEP and PEP/LVET) exhibited excellent correlations with measures of contractility in subjects with normal left ventricles or cardiac disease confined to the left ventricle.
Why the study?
Do systolic time intervals (PEP and PEP/LVET) accurately reflect left ventricular myocardial contractility in normal subjects and patients with cardiac disease?
Population
14 normal subjects and 56 patients with cardiac disease (n=70)
Design
Cross-sectional
Authors
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Supports systolic time intervals for noninvasive LV contractility assessment in isolated disease; leaves open prospective validation and outcome studies.
Observational (n=70)
Do systolic time intervals (PEP and PEP/LVET) accurately reflect left ventricular myocardial contractility in normal subjects and patients with cardiac disease?
Systolic time intervals (PEP and PEP/LVET) are valid measures of left ventricular contractility in patients with normal ventricles or isolated left ventricular disease.
Ahmed et al. (1972) conducted an observational in Cardiac disease (n=70). Systolic time intervals (PEP and PEP/LVET) vs. Direct measures of LV performance and contractility was evaluated on Correlation of PEP and PEP/LVET with measures of LV performance and contractility. Systolic time intervals (PEP and PEP/LVET) exhibited excellent correlations with measures of contractility in subjects with normal left ventricles or cardiac disease confined to the left ventricle.
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