Population
One 41-year-old male patient with hypertrophic cardiomyopathy carrying a G3755A heterozygote mutation in MYH6
Design
In vitro cell line generation study
Authors
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May facilitate mechanistic studies of MYH6-mutant HCM in vitro; hypothesis-generating and leaves open clinical translation.
The successful generation of an iPSC line from a patient with hypertrophic cardiomyopathy and a MYH6 mutation provides a valuable in vitro model for studying the disease mechanisms.
Wang et al. (2020) studied this question.
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