Answers are grounded in this paper and cite their sources.
receptor modulators) in relation to pharmacodynamic properties and clinical outcomes. We then suggest a drug discovery pathway focused on physiological parameters. It is our opinion that this approach would dramatically decrease the lethality of overdose and improve outcomes of treatments for pain, anxiety, and withdrawal from alcohol, benzodiazepines, and opioids.
No takes yet. Share an insight, caveat, or question.
Carry et al. (2025) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: