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Epidemiological studies typically rely on exposure assessments based on ambient PM 2.5 concentrations at participants’ home addresses. However, these approaches neglect personal exposures indoors and across different non-residential microenvironments. To address this problem, our study combined low-cost sensors and GPS to conduct two-week personal PM 2.5 monitoring in 168 adults recruited from the Washington State Twin Registry between 2018 and 2021. PM 2.5 mass concentration, size-resolved particle number concentration, temperature, humidity, and GPS coordinates were recorded at 1-minute intervals, providing 5,161,737 datapoints. We used GPS coordinates and a processing algorithm for automatic classification of microenvironments, including seven land use types and vehicles, and time spent indoors/outdoors. The low-cost sensors were calibrated in-situ, using regulatory monitoring data within 600 m of participants’ outdoor measurements (R 2 = 0.93). A linear mixed model was used to estimate the associations of multiple spatiotemporal factors with personal exposure concentrations. The average PM 2.5 exposure concentration was 8.1 ± 15.8 μg/m 3 for all participants. Indoor exposure concentration was higher than outdoor exposure level, and indoor exposure dose contributed 77% to the total exposure. Exposures in residential and industrial land use had a higher concentration than in other areas, and accounted for 69% of the total exposure dose. Furthermore, personal exposure concentration was the highest during winter and evening hours, possibly due to cooking and heating-related behaviors. This study demonstrates that personal monitoring can capture spatiotemporal variations in PM 2.5 exposure more accurately than home-based approaches based on ambient air quality, and suggests opportunities for controlling exposures in certain microenvironments. • 168 twin-cohort participants completed two-week personal PM 2.5 and GPS monitoring. • Personal PM 2.5 exposure varied across space and time, implying variable health risks. • Indoor exposure had higher exposure concentration and exposure dose than outdoor. • Residential/industrial PM 2.5 concentration was higher based on regression analysis. • Home-based exposure assessment cannot capture actual personal exposure patterns.
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Liu et al. (2025) studied this question.
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