Use of the capture-recapture technique to evaluate the completeness of systematic literature searches: Table 1

CommentThe presence of HIV in semen has been well documented,2 3 but the relation between the viral load in semen and peripheral blood CD4 counts is not a simple one.'No studies have looked at the serial viral load of genital fluids during treatment for other sexually transmitted diseases, although a single case report has suggested that chlamydial urethritis may increase shed- ding of HIV-1 in the semen.4Our results help explain how transmission of HIV may be facilitated by concomitant sexually transmitted diseases and add further support for an aggressive approach to treating sexually transmitted diseases in HIV infected patients, as a means of reducing transmission of HIV and for reinforcing the benefits of using condoms.5