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This article explores evidence regarding sex and gender differences in schizophrenia and their implications for treatment. It highlights key differences in age of onset, symptom presentation, and cannabis use, while examining methodological limitations in existing research. Men tend to have an earlier onset and more severe negative symptoms, often linked to cannabis use, while women show delayed onset and are influenced by oestrogen levels. The inconsistent findings on symptom presentation underline the need for further robust research. The article emphasises tailoring treatment approaches to genderspecific needs, such as early detection and substance abuse programmes for men and hormone-focused care for women.
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Himanshi Naredi (2025) studied this question.
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