Key result
Following radiofrequency ablation for atrioventricular reentrant tachycardia, having two accessory pathways or intermittent ventricular pre-excitation increased the risk of relapse by 6 and 9 times.
Why the study?
What are the risk factors for recurrence and complications following radiofrequency catheter ablation for atrioventricular reentrant tachycardia in children and adolescents?
Observational (n=213)
What are the risk factors for recurrence and complications following radiofrequency catheter ablation for atrioventricular reentrant tachycardia in children and adolescents?
Effect estimate: RR 9.0
Multiple accessory pathways and intermittent ventricular pre-excitation are significant risk factors for AVRT recurrence after ablation in pediatric patients, with complications occurring exclusively in younger children.
May support targeted post-ablation surveillance in high-risk youth; leaves open whether risk stratification improves outcomes in prospective studies.
BACKGROUND: To compare potential risk factors for complications and recurrence after radiofrequency catheter ablation in symptomatic atrioventricular reentrant tachycardia in children and adolescents. METHODS: We retrospectively reviewed the data of 213 consecutive patients with symptomatic atrioventricular reentrant tachycardia who underwent both electrophysiological study and radiofrequency catheter ablation, divided these patients into two groups, children (age < 12 years) and adolescents (12 < or = rage, 18 years), and compared the location of the accessory pathway, success rate, recurrence rate, complications, presence of congenital heart disease, presence of intermittent ventricular pre-excitation, and presence of Wolff–Parkinson–White syndrome in the two groups. RESULTS: The position of the accessory pathway was mostly right sided in children (61.3%) and left sided in adolescents (61.5%). Children had significantly more congenital heart disease than adolescents (6.4% versus 0.8%). Univariate analysis showed children or adolescents with right-sided accessory pathways to be 6.84 times and those with accessory pathways on both sides of the septum 25 times more likely to relapse than those with a single accessory pathway. Multivariate analysis indicated that children or adolescents with two accessory pathways were six times, and those with intermittent ventricular pre-excitation nine times more at risk of relapsing following radiofrequency ablation than those with single accessory pathways. All five complications occurred in children. CONCLUSIONS: The findings suggest that the position and number of accessory pathways and presence of intermittent ventricular pre-excitation are related to risks of recurrence of atrioventricular reentrant tachycardia in children and adolescents.
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Chen et al. (2013) conducted an observational in symptomatic atrioventricular reentrant tachycardia (n=213). Radiofrequency catheter ablation vs. Single accessory pathway / no pre-excitation was evaluated on Recurrence of atrioventricular reentrant tachycardia (RR 9.0). Following radiofrequency ablation for atrioventricular reentrant tachycardia, having two accessory pathways or intermittent ventricular pre-excitation increased the risk of relapse by 6 and 9 times.
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