Key result
Supraventricular arrhythmias during pulmonary endarterectomy for CTEPH are linked to increased ischemic stroke and prolonged ventilation.
Why the study?
The features of the early postoperative period in patients with chronic thromboembolic pulmonary hypertension and concomitant supraventricular arrhythmias were not well characterized.
Do concomitant supraventricular arrhythmias worsen early postoperative outcomes in patients with CTEPH undergoing pulmonary endarterectomy?
Cohort (n=133)
Do concomitant supraventricular arrhythmias worsen early postoperative outcomes in patients with CTEPH undergoing pulmonary endarterectomy?
Concomitant supraventricular arrhythmias in CTEPH patients undergoing pulmonary endarterectomy are associated with a more complicated early postoperative course, including increased risk of ischemic stroke and prolonged hospitalization.
May warrant closer monitoring in CTEPH endarterectomy patients with arrhythmias; leaves open causality and need for prospective confirmation.
Objective. To study early postoperative period in patients with chronic thromboembolic pulmonary hypertension (CTEPH) with concomitant supraventricular arrhythmias. Material and methods. We analyzed 133 patients with CTEPH who were admitted for pulmonary endarterectomy. Mean age was 52.8 (43.2—64.1) years. The 1st group (31 people) consisted of patients with concomitant supraventricular arrhythmias (atrial fibrillation, sinus tachycardia), the 2nd group (102 people) — without rhythm disturbances. Between-group analysis of clinical and functional data, as well as early postoperative period was carried out. Results. In the general group of patients, supraventricular rhythm disturbances were observed in 23.3% of cases. According to clinical data, the 1st group was characterized by older age (p=0.03), concomitant type 2 diabetes (p<0.001), higher incidence of obesity (p<0.001) and higher comorbidity index (p=0.02). Early postoperative period was more severe in the 1st group, where we observed ischemic stroke (p=0.01), larger proportion of patients with prolonged mechanical ventilation (p=0.03) and prolonged in-hospital period (p=0.04) compared to the 2nd group. There were no between-group differences in in-hospital mortality (p=0.19). Conclusion. Concomitant supraventricular arrhythmias in patients with CTEPH are associated with more severe early postoperative period with registration of ischemic stroke, larger proportion of patients with prolonged artificial ventilation and in-hospital period compared to patients without concomitant supraventricular arrhythmias. There was no effect of concomitant supraventricular arrhythmias on in-hospital mortality.
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Клинкова et al. (2025) conducted a cohort in Chronic thromboembolic pulmonary hypertension (CTEPH) (n=133). Concomitant supraventricular arrhythmias vs. No rhythm disturbances was evaluated on Early postoperative period outcomes (ischemic stroke, prolonged mechanical ventilation, prolonged in-hospital period, in-hospital mortality). Concomitant supraventricular arrhythmias in CTEPH patients undergoing pulmonary endarterectomy were associated with increased ischemic stroke (p=0.01) and prolonged mechanical ventilation (p=0.03).
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