The PHQ-9 (cut-off ≥11) and PHQ-2 (cut-off ≥3) effectively screened for major depressive disorder, with the PHQ-9 demonstrating an overall accuracy of 0.81 (sensitivity 0.76, specificity 0.81).
Case-Control (n=521)
No
Do the PHQ-9 and PHQ-2 accurately screen for major depressive disorder in Japanese primary care outpatients?
The PHQ-9 and PHQ-2 are useful screening instruments for major depressive disorder in Japanese primary care, with optimal cut-offs of ≥11 and ≥3, respectively.
Effect estimate: Accuracy 0.81 (95% CI 0.77-0.84)
OBJECTIVE: The Patient Health Questionnaire (PHQ-9) is a self-report questionnaire commonly used to screen for depression, with ≥8-11 generally recommended as the cut-off. In Japan, studies of the validity of the PHQ-9 and PHQ-2 have been limited. In this study, we examined the utility of the PHQ-9 and PHQ-2 at an outpatient clinic in a Medical University Hospital in Japan. METHODS: New consecutive outpatients were included in the study. We administered the PHQ-9 to 574 patients, and acquired complete PHQ-9 and PHQ-2 data for 521 patients. Major depressive disorders were diagnosed according to the DSM-IV-TR. RESULTS: Forty-two patients were diagnosed with major depressive disorders. The mean PHQ-9 (15.7) and PHQ-2 (3.8) scores of the patients with major depressive disorders were significantly higher than the scores of the patients without depression (6.0 (PHQ-9) and 1.8 (PHQ-2)). The best cut-off points for the PHQ-9 and PHQ-2 summary scores were ≥11 (sensitivity 0.76, specificity 0.81) and ≥3 (sensitivity 0.76, specificity 0.82), respectively. No relationship was observed between the age and PHQ-9 scores. CONCLUSION: The PHQ-9 and PHQ-2 were useful instruments for screening for major depressive disorders. The best cut-off point for the PHQ-9 summary score should be ≥11 to detect depression in the primary care setting in Japan.
Suzuki et al. (Thu,) conducted a case-control in Major Depressive Disorder (n=521). PHQ-9 and PHQ-2 vs. MINI structured diagnostic interview (DSM-IV-TR) was evaluated on Overall accuracy of PHQ-9 (cut-off ≥11) for major depressive disorder (Accuracy 0.81, 95% CI 0.77-0.84). The PHQ-9 (cut-off ≥11) and PHQ-2 (cut-off ≥3) effectively screened for major depressive disorder, with the PHQ-9 demonstrating an overall accuracy of 0.81 (sensitivity 0.76, specificity 0.81).