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May 27, 2021MedicinaOpen Access

The Potential Mechanisms of High-Velocity, Low-Amplitude, Controlled Vertebral Thrusts on Neuroimmune Function: A Narrative Review

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Key result

High-velocity vertebral thrusts may modulate immune function via changes in CNS proprioceptive processing.

Why the study?

Mechanisms linking high-velocity, low-amplitude (HVLA) controlled vertebral thrusts to neuroimmune function and their clinical implications were unclear.

Do high-velocity, low-amplitude controlled vertebral thrusts modulate neuroimmune function?

Design

Narrative review

Authors

HHHeidi HaavikINImran Khan NiaziNKNitika Kumari

Discussion

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Member takes

Overview

May support neuroimmune modulation hypothesis; leaves open clinical relevance and need for prospective trials.

Structured PICO

Do high-velocity, low-amplitude controlled vertebral thrusts modulate neuroimmune function?

P
Population
23 published papers exploring the impact of HVLA controlled vertebral thrusts on neuroimmune markers
I
Intervention
High-velocity, low-amplitude (HVLA) controlled vertebral thrusts
O
Outcome
Neuroimmune function and markers (neuropeptides, inflammatory markers, endocrine markers)surrogate

HVLA controlled vertebral thrusts may modulate immune mediators through changes in proprioceptive processing within the central nervous system, though clinical relevance remains unknown.

Limitations

  • It is not yet known whether HVLA controlled vertebral thrusts have a clinically relevant impact on immunity.
  • It is not yet known whether HVLA controlled vertebral thrusts have a clinically relevant impact on immunity

Cite This Study

Haavik et al. (2021) conducted a review in Neuroimmune function. High-velocity, low-amplitude (HVLA) controlled vertebral thrusts was evaluated on Impact on neuroimmune markers. High-velocity, low-amplitude controlled vertebral thrusts have the potential to modulate immune function through changes in proprioceptive processing within the central nervous system.

synapsesocial.com/papers/6a10df4c39dd87f6d0ee7ab9https://doi.org/10.3390/medicina57060536
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