Why the study?
Does antithrombotic prophylaxis with long term warfarin or aspirin reduce thromboembolic risk in patients with atrial fibrillation?
Does antithrombotic prophylaxis with long term warfarin or aspirin reduce thromboembolic risk in patients with atrial fibrillation?
Long-term antithrombotic prophylaxis with warfarin or aspirin is recommended to reduce thromboembolic risk in patients with atrial fibrillation, guided by clinical risk stratification.
Affirms antithrombotic benefit in AF from aggregated data; leaves open optimal strategies with contemporary agents.
Antithrombotic prophylaxis with long term warfarin or aspirin reduces thromboembolic risk in atrial fibrillation. Identification, risk assessment, and regular review of all patients with atrial fibrillation should be routine in general and hospital practice. Risk stratification is easily performed on clinical grounds--echocardiography may refine it.
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Lip et al. (1996) studied this question.
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