Key result
Cine MR imaging with myocardial tagging in 16 normal volunteers demonstrated significant nonuniformity of left ventricular contraction across 7 LV locations, including a transmural gradient.
Observational (n=16)
Cine MR imaging with myocardial tagging demonstrates significant normal nonuniformity in left ventricular regional contraction, which may be associated with myocardial fiber architecture and wall stress.
Answers are grounded in this paper and cite their sources.
Describes normal LV contraction nonuniformity; extends physiologic reference data but leaves open disease-state implications.
Purpose: To identify the normal performance of left ventricular (LV) regional contraction using cine MR imaging with presaturation myocardial tagging.Material and Methods: Sixteen normal volunteers were examined on a 1.5 T MR system with tagging cine sequences. Tags were applied at end-diastole as 2 parallel black lines on short-axis and 4-chamber sections, and the fractional shortenings were calculated at 7 LV locations.Results: The following results were obtained with significance: a transmural gradient of contractility in the short-axis section; prolonged late-systolic endocardial shortening and epicardial early termination in the free wall; initial delay of shortening in the anterior wall; apical predominance of contractility; predominance of circumferential shortening in the free wall and of meridional shortening in the septum. These findings could be associated with myocardial fiber architecture, presumed wall stress and temporal asynergy of excitation.Conclusion: Cine MR imaging with myocardial tag...
No takes yet. Share an insight, caveat, or question.
Naito et al. (1996) conducted an observational in Healthy volunteers (n=16). Cine MR imaging with presaturation myocardial tagging was evaluated on Fractional shortenings at 7 LV locations. Cine MR imaging with myocardial tagging in 16 normal volunteers demonstrated significant nonuniformity of left ventricular contraction across 7 LV locations, including a transmural gradient.
Synapse has enriched 10 related papers. Consider them for comparative context: