What question did this study set out to answer?

To determine whether phobic anxiety symptoms are associated with decreased heart rate variability in men free of coronary artery disease and diabetes.

May 1, 1995The American Journal of CardiologyOpen Access

Decreased heart rate variability in men with phobic anxiety (data from the normative aging study)

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Why the study?

Does phobic anxiety reduce heart rate variability in men free of coronary artery disease and diabetes?

Population

581 men, aged 47 to 86 years, enrolled in the Normative Aging Study who were free of coronary artery disease…

Comparison

Higher levels of phobic anxiety vs Lower levels of phobic anxiety

Design

Cohort

Authors

IKIchiro KawachiHarvard University DSDavid SparrowBroad Institute PVPantel VokonasGeneral / Preventive / Lipids

Discussion

Member takes

Implication

Phobic anxiety may signal SCD risk via autonomic imbalance; hypothesis-generating for trials of anxiety reduction on HRV.

Key Points

To determine whether phobic anxiety symptoms are associated with decreased heart rate variability in men free of coronary artery disease and diabetes.
Evaluated 581 men aged 47 to 86 years enrolled in the Normative Aging Study without coronary artery disease or diabetes.
Measured phobic anxiety symptoms via the Crown-Crisp index and assessed heart rate variability under standardized paced deep breathing (6 breaths per minute) using the standard deviation and range of heart rate over 1 minute.
Men reporting higher phobic anxiety demonstrated significantly elevated resting heart rates (p = 0.025 for linear trend).
After adjusting for age, mean heart rate, and body mass index, higher phobic anxiety remained significantly associated with lower heart rate variability by standard deviation of heart rate (p = 0.03 for linear trend) and maximal minus minimal heart rate (p = 0.03 for linear trend).

Structured PICO

Does phobic anxiety reduce heart rate variability in men free of coronary artery disease and diabetes?

Population

581 men, aged 47 to 86 years, enrolled in the Normative Aging Study who were free of coronary artery disease and diabetes.

Intervention

Higher levels of phobic anxiety (assessed using the Crown-Crisp index)

Comparator

Lower levels of phobic anxiety

Outcome

Heart rate variability (measured by the SD of HR and the maximal minus minimal HR over 1 minute during paced deep breathing)surrogate

Higher levels of phobic anxiety are associated with reduced heart rate variability in men without coronary artery disease or diabetes, suggesting altered cardiac autonomic control that may increase the risk of sudden cardiac death.

Cite This Study

Kawachi et al. (1995) studied this question.

synapsesocial.com/papers/6a11030ecd70b138bf1a007e https://doi.org/10.1016/s0002-9149(99)80680-8

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Decreased heart rate variability in men with phobic anxiety (data from the normative aging study)

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Decreased heart rate variability in men with phobic anxiety (data from the normative aging study)

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider