November 29, 2009Metabolic Syndrome and Related Disorders

Prevalence and Correlates of Diabetes in South Asian Indians in the United States: Findings From the Metabolic Syndrome and Atherosclerosis in South Asians Living in America Study and the Multi-Ethnic Study of Atherosclerosis

Q: What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Type 2 Diabetes (n=6676). Intervention: South Asian Indian ethnicity vs. Whites, Latinos, African Americans, and Chinese Americans (MESA cohorts). Primary outcome: Odds of diabetes (Whites vs South Asian Indians) (OR 0.29, 95% CI 0.17-0.49).

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Key result

South Asian Indians had a 29% prevalence of diabetes and significantly higher adjusted odds of diabetes compared to whites (OR 0.29 for whites vs Indians) and Latinos.

Why the study?

Do South Asian Indians in the United States have a higher prevalence of diabetes compared to other ethnic groups?

Study Design

Type

Cross-Sectional (n=6,676)

Multicenter

Structured PICO

Do South Asian Indians in the United States have a higher prevalence of diabetes compared to other ethnic groups?

Population

150 South Asian Indians (ages 45-79) in California, and participants from other U.S. ethnic groups in the Multi-Ethnic Study of Atherosclerosis (MESA)

Comparator

Whites, Latinos, African Americans, and Chinese Americans from the MESA study

Outcome

Prevalence of Type 2 diabetes (classified by fasting plasma glucose ≥126 mg/dL, 2-h postchallenge glucose ≥200 mg/dL, or use of hypoglycemic medication)

Main Result

Effect estimate: OR 0.29 (95% CI 0.17-0.49)

Limitations

Small sample size of the MASALA pilot study
Cross-sectional nature of the study limits causal inference
MASALA participants were sampled from a non-MESA site, which may affect comparability
Fasting glucose was measured in different laboratories for the MASALA and MESA studies

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

May support targeted diabetes screening in South Asian Indians; leaves open confirmation in larger US cohorts.

Cite This Study

Kanaya et al. (2009) conducted a cross-sectional in Type 2 Diabetes (n=6,676). South Asian Indian ethnicity vs. Whites, Latinos, African Americans, and Chinese Americans (MESA cohorts) was evaluated on Odds of diabetes (Whites vs South Asian Indians) (OR 0.29, 95% CI 0.17-0.49). South Asian Indians had a 29% prevalence of diabetes and significantly higher adjusted odds of diabetes compared to whites (OR 0.29 for whites vs Indians) and Latinos.

synapsesocial.com/papers/6a1104e5a334b8d43a16858f https://doi.org/10.1089/met.2009.0062

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Prevalence and Correlates of Diabetes in South Asian Indians in the United States: Findings From the Metabolic Syndrome and Atherosclerosis in South Asians Living in America Study and the Multi-Ethnic Study of Atherosclerosis

Study Design

Structured PICO

Main Result

Limitations

Discussion

Implication

Cite This Study

Prevalence and Correlates of Diabetes in South Asian Indians in the United States: Findings From the Metabolic Syndrome and Atherosclerosis in South Asians Living in America Study and the Multi-Ethnic Study of Atherosclerosis

Study Design

Structured PICO

Main Result

Limitations

Discussion

Implication

Cite This Study

Also Consider

Also Consider