Key result
Older age, antidepressants, and antipsychotics are linked to higher metabolic syndrome prevalence in refugees with PTSD.
Why the study?
What is the prevalence of metabolic syndrome in refugees with PTSD, and is it associated with age, sex, and psychotropic medication use?
Cross-Sectional (n=219)
No
What is the prevalence of metabolic syndrome in refugees with PTSD, and is it associated with age, sex, and psychotropic medication use?
Metabolic syndrome is highly prevalent in refugees with PTSD and is associated with older age and psychotropic medication use, highlighting the need for targeted metabolic screening and interventions in this vulnerable population.
PURPOSE: This study is the first to examine the prevalence of metabolic syndrome (MetS) and its four components (hypertension, dyslipidaemia, dysglycaemia and obesity) in a population of trauma-affected refugees. We also examined whether MetS was associated with age, sex and medication use. MATERIALS AND METHODS: Data were collected from a cohort of refugees with PTSD who participated in a randomised controlled trial (RCT) at the Competence Centre for Transcultural Psychiatry (CTP), Denmark. The cohort comprised 110 men and 109 women (mean age = 44 years, SD = 10.4) predominantly from the Middle East, with additional representation from Asia, Africa, and Eastern Europe. MetS was defined according to the Danish medical handbook (fasting glucose was substituted with HbA1c) and Chi-square tests were utilised to examine associations between MetS and age, sex and use of antidepressants and antipsychotics. CONCLUSIONS: In a cohort of refugees with PTSD, the prevalence of MetS was elevated and associated with older age, and the use of antidepressants and antipsychotics. Among the four MetS components, dyslipidaemia was particularly prevalent in men, highlighting the need for targeted interventions.
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Smidl-Jørgensen et al. (2025) conducted a cross-sectional in Post-traumatic stress disorder (PTSD) (n=219). Older age and psychotropic medication use (antidepressants and antipsychotics) vs. Younger age and no psychotropic medication use was evaluated on Prevalence of metabolic syndrome (MetS) and its components (p=< 0.001). Older age and the use of antidepressants and antipsychotics were associated with an elevated prevalence of metabolic syndrome in refugees with PTSD (P<0.001).
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