Key result
Preoperative obstructive spirometry and respiratory disease linked to ~150% higher in-hospital mortality.
Why the study?
Obstructive lung disease may affect surgical mortality after cardiac surgery, but a pre-existing diagnosis may not be present in all individuals with obstruction.
Does preoperative spirometry assessment and the presence of undiagnosed or misdiagnosed obstructive lung disease impact in-hospital mortality following cardiac surgery?
Observational (n=16,906)
No
Does preoperative spirometry assessment and the presence of undiagnosed or misdiagnosed obstructive lung disease impact in-hospital mortality following cardiac surgery?
A significant proportion of cardiac surgery patients have undiagnosed obstructive lung disease on spirometry, and pre-existing respiratory diagnosis or spirometric obstruction is associated with higher in-hospital mortality.
Misdiagnosis-linked mortality warrants careful spirometry review in cardiac surgery; leaves open whether accurate diagnosis improves outcomes.
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Peat et al. (2026) conducted an observational in Cardiac surgery (n=16,906). Obstructive spirometry and/or respiratory disease diagnosis vs. No respiratory diagnosis and no obstruction on spirometry was evaluated on In-hospital mortality. Preoperative obstructive spirometry and a respiratory disease diagnosis were associated with higher in-hospital mortality (4.5%) compared to patients with neither (1.8%).
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