Why the study?
Does Doppler ultrasound detect preclinical changes in arterial wall compliance and pulse-wave damping in non-insulin-dependent diabetic men compared to nondiabetic controls?
Does Doppler ultrasound detect preclinical changes in arterial wall compliance and pulse-wave damping in non-insulin-dependent diabetic men compared to nondiabetic controls?
Doppler ultrasound can detect preclinical changes in arterial wall compliance and pulse-wave damping in diabetic patients prior to the onset of clinical peripheral arterial disease.
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May support Doppler detection of early arterial changes in diabetes; leaves open impact on outcomes or screening.
Doppler ultrasound was used to detect early changes in arteries of the legs by two independent techniques. Pulse-wave velocity was measured to calculate arterial wall compliance and Fourier analysis was used to measure damping of the pulse-wave forms. Ten non-insulin-dependent diabetic men with no clinical evidence of peripheral arterial disease had significantly lower compliance and greater pulse-wave damping than 10 matched nondiabetic control subjects. There was a good correlation between the results for the two different techniques.
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Lo et al. (1986) studied this question.
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